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Tadalafil. How safe is it?

What do we know about Tadalafil? Tadalafil is an active component of many drugs that treat ED. A PDE-5 inhibitor, which has many advantages over other popular contents of blue pills. For instance, its length of action is 36 hours, it works regardless of taking before or after meal, and it starts working in 20-30minutes after uptake.

Moreover, it is unique feature is the ability to chose between two forms, and two ways of taking it. It is available for daily taking and for taking as needed. The dose for daily use is much smaller than the other. 2.5mg vs 10 or 20mg. The most famous brand name of it is Cialis, but there are also a lot of cheaper generics (Vidalista, Megalis, Tadacip, Tadagra, Tadalista), that work the same. Its history starts with being one of the first drugs on market healing erectile dysfunction. The first manufacturer that pulled it to trades was Eli Lily, that gave it the Cialis brand name. In 2003 it got FDA approval license. In 2017, the patent of Cialis ended, in result, we have a lot of much cheaper alternatives of it, and we are finally able to save money on it.

To whom is Tadalafil usually prescribed? It is used both for pulmonary hypertension treatment and ED treatment. There exist two ways of taking it for ED. In situational usage for ED it is considered to be 10mg pill once a day before intercourse. On an everyday basis, ED is treated with 2.5mg once a day. It`s better to take it at the same time, but that`s not obligatory. If it doesn`t work for you, it can be leveled up to 5 as minimum, 20 as maximum dose. In cases of PH, an elephant doses of 40mg once a day is a common prescription. Sometimes it is also used for Benign Prostatic Hyperplasia in 5mg-per-day regime.

Is it safe?

It is proved to be saved by many studies. One of them is the study of a multicentre, open-label, 24-month extension tadalafil trial at Università Vita e Salute San Raffaele in Milan. It has shown that Tadalafil at doses of 5, 10, or 20mg taken as needed up to once daily for 18 to 24 months was safe and well tolerated. Another study, led by Fundacíon para la Investigacíon y el Desarrollo en Andrología in Madrid, has taken as an object tadalafil`s effect on men with diabetes of second and third types. This study has shown that Tadalafil at 10 and 20 mg improved erectile function irrespective of the type of diabetes, presence of microvascular complications, or type of diabetes treatment. It was both safe and effective, though rare mild side effects were reported.

Thus, a demonstrated long-term safety should have convinced people. However, if everything is safe, why might you find several provocative utterances while searching the Internet?

Are there any factual reasons to suspect tadalafil of harmfulness?
Probably, Tadalafil is been biased against. As if you read the information list, you may find various contraindications and warnings, and a mass of harmful conditions described may frighten any pilgarlic.

Let us see some of these horrors:

Risk factors of tadalafil take going wrong:
• Being prone of priapism, in simple words, of long and painful erection
• heart disease or heart rhythm problems
• a heart attack or stroke
• angina, high or low blood pressure
• pulmonary veno-occlusive disease
• liver or kidney disease (or if you are on dialysis)
• vision loss, when there are some inherited risk factors
• a bleeding disorder
• sickle cell anemia, multiple myeloma, or leukemia
• a physical deformity of the penis
• a stomach ulcer

Are there any dangerous side effects for those who are not prone of all the above?

Typical side effects are:
1) headache
2) flushing
3) nausea, upset stomach
4) stuffy nose
5) muscle pain in back, arms or legs

There won`t be any severe side effects if you don`t have any risk factors. ALLERGY WARNING! Perhaps, you may harm yourself if you have allergy to this drug. It would be better to check if you have it in advance. Ask your doctor, what tests can you pass to reveal if you have it or not.

Typical allergic reactions are:

1) difficulty breathing 2) swelling of your face / lips / tongue / throat

Conclusion: what to check before taking?

1) If you have any of risk factors or not
2) If you have allergy or not
If the tests are coming negative, or if your medical consultant says you are all right, you can undoubtedly use it.